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Junko Takada nackt - Diverse metabolic reactions activated during 58









Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood.


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Urate was the most abundant nucleoside or nucleotide detected during fasting Table and Fig.



All participants remained healthy and manifested no adverse symptoms during the study.



Cold Spring Harb Protoc 2016, pdb.



This non-targeted comprehensive analysis of human blood disclosed large-scale shifts in blood metabolite profiles during 58 hr of fasting, comprising significant changes in 46 metabolites, including 32 previously unreported fasting markers Table.



We performed non-targeted, accurate semiquantitative metabolomic analysis of human whole blood, plasma, and red blood cells during 34—58 hr fasting of four volunteers.


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Metabolism-Clinical and Experimental 25, 1287—1302 1976.



In each panel, p-values are presented to show the significance of serial change until 58 hr by Friedman test.





In each panel, p-values are presented to show the significance of serial change until 58 hr by Friedman test.






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Description: All of the 46 compounds increased, except for aspartate 0.

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Quantification of blood metabolites from 4 volunteers during prolonged fasting.
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This non-targeted comprehensive analysis of human blood disclosed large-scale shifts in blood metabolite profiles during 58 hr of fasting, comprising significant changes in 46 metabolites, including 32 previously unreported fasting markers Table.
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Human metabolic individuality in biomedical and pharmaceutical research.

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